Interesting thread!
Been GMing since March, and we've had one party death - the decker got involved in a nasty gunfight with someone dishing out 6 round bursts, while the sammy was a few blocks away. He chose not to burn edge, but to create a new character he'd been thinking about for a while.
I've not seen character death affect the story overly, the adventure tends to drive the plot along. I guess it depends on how crucial to the plot a particular character is. I do try to write adventures around character backgrounds, especially their contacts and friendships, so I could see this causing issues, but it hasn't so far.
I think an issue where character death can be a problem is if a new player is transitioning from a system such as D&D, with a very different combat system. Overconfidence can kill real quick. Also if a player doesn't understand the situation they are in, eg. we had a new player rip off a flamethrower spell in the middle of yakuza owned nightclub, which went south fast, but didn't actually kill any runners. In either of these situations, the player may see their resulting bludgeoning, or death, as "unfair" and a more yielding GM might be tempted to let them slip away, due to their lack of understanding. However, my view is that if the world responds realistically (and robustly) they will very quickly see the error of their ways, and amend their behaviour.