Well, that depends on your GM, I guess; he could tell you, or not. "You see a grenade coming at you" doesn't really tell you if it's live or not, so it might be wise to get the hell out of dodge.
That's more of a narrative thing, and I presume you're talking about game mechanics.
If you look at page 421 under Wireless Bonuses, you'll see the following:
"If there is a Noise Rating from a situation that is greater than the item’s Device Rating, not including distance, the item temporarily loses its wireless functionality (see Noise, p. 230)."
There's some contention about whether a wireless grenade is actually wireless, because the way the above text is written it can be interpreted as the grenade simply losing it's Wireless Bonus, which is that you can detonate it even if you don't have a DNI. Some people take that to mean a grenade affected by noise greater than it's device rating can thus still be detonated if you have a DNI. I don't agree with this interpretation, but that's just me.
Basically, if you get a Rating 6 Area Jammer, any device (with the exception of those you designate, if you use the Jammer's wireless bonus) within 5m of you will be affected by a Noise Rating of 6. Anything from 6 to 10m of you will be affected by a Noise Rating of 5, and so on and so forth.
On the same page at the very top you'll find a list of device types and common Device Ratings. Basically, you can probably make things interesting for the opposing Decker by running up to him with a Rating 6 Area Jammer strapped to your chest.
[EDIT]
Ninja's by Michael
