..OK caught about half of tonight's live play session (was busy in the kitchen).
When the sidebar chat moved to purchasing/upgrading skills I found another major downside. Instead of it taking 2 Karma x skill rating to learn/improve a skill, it now takes 5 Karma. Furthermore the time span is increased from days x rating (1 - 4) and weeks x rating (5+) to one full month x skill rating. This will really stifle character advancement particularly in a homebrew to the point your character will be relatively "static" for a long time. It will also likely mean few characters will take anything above a Low lifestyle as it could get costly (increasing your firearms skill to say, 6 suddenly costs you 12,000¥ at a low lifestyle plus the training cost). So much for what you made on that last run that you wanted to put away for that new piece of chrome or wetware.
The time factor will not have as much an impact in missions play as you can take as much downtime as needed between sessions however the resources impact will still be there. For example my character Leela who has a middle lifestyle, getting that rating 6 in a single skill would cost 30 Karma and 30,000¥ (about the price for a degree at a state college!).
The way it was explained is that all skills are now skill groups and sub-classes (like say Pistols) are now specialisations that still require you to have the base group skill. It wasn't explained how much it cost on time and Karma for specialisations and how far one could increase them (I came away with the impression that you need to raise the core skill first to improve the specialisation further). If Karma awards are about the same as they currently are in 5E, it would mean very, very slow character advancement overall. I don't know how others feel, but if I devote weeks if not months to playing and really don't see my character improving very much, I'll bag it and go find some other way to spend my time that is more rewarding (or just stay with 5E).