If the infection is only effective while the ghoul is alive (as is the case in prior editions, i.e. infection power is based on essence) then you could take the depowered virus and use it as an inoculation. Once you overcome the weakened virus, you have an immunity to it.
If the infection ability extends beyond the life of the ghoul, like Anthrax which can stay dormant for years, then you've got the issue of anything the ghoul has ever touched is now contagious.
Of course, the real reason that you can't contaminate everyone that easily is that A) HMHVV is destroyed by the UV of the sun and B) the Green river is so toxic and polluted that people don't go near it and the virus couldn't survive the bath.
A couple issues with the Krieger strain is the moving goal posts. For the other forms of HMHVV (vampirism) it is passed on via the Infection power. For ghouls it is passed on with the Pestilence power. In 3rd Ed. Pestilence was Unmodified body vs. Essence - 2. For a stock ghoul, with essence 5, that means a 3. The Stock average person with 3 body would have to roll 2 or less 3 times to get infected. That's about 4% chance. SR companion moved those goal posts up to straight up Essence. So now the average person had to roll 5 or higher, which means about 30% infection rate. I've got no idea how it is in 4th edition, but prior to power creep, the average person should only have a 4% chance of being infected.