After a few weeks of introducing my players to Shadowrun 5E after it released (they are long time D&D/Pathfinder players with no experience in Shadowrun), we finally took the dive into the game last night.
It turned out pretty good. Most of them were ready and excited to play. The group is made up of a Human street samurai, Human face/rigger, dwarf technomaner, Troll hermetic mage and a Human mystic adept (with the applicable errata for power points). I opted to just run them through Season 4 to get a feel for the world and to understand what kind of runs will come their way. We started with Copycat Killer and they actually almost completed the full run (just short of confronting Shawn Walker) and they managed not to get themselves killed or hated by the Ork Underground.
There weren't too many instances of players being left out. I did find myself having to make a mental note of making sure to re-read some of the ways to utilize contacts again for their legwork purposes.
The single encounter they had ended very quickly and this is where I was most surprised from Shadowrun and D&D combat. The rigger had a drone lay down suppressive fire on the group of gangers that were hired to take out the runners and he ended up hitting all of them (Yes, all the gangers failed the Reaction + Edge test, granted they were mooks). The mage threw out a Powerball after that and essentially knocked them all out and one of the gangers died from overflow. I'm probably going to upping some of the difficulty for them as the combat associated people are pretty monstrous and I know they enjoy fighting encounters.
Not too many problems and a lot of them are enjoying the game immensely so far.