Snow, if you're reading this, turn back now. You know who you are

So a year or so ago I started running Shadowrun 4th for my group, but put it on hiatus until now, when we're gonna be continuing with 5th edition. I've had some bare bones ideas for a campaign arc but I could use some help in refining the story and bouncing off my ideas to you folks who are far more SR savvy than I am.
So my idea was something called the Matrioshka Project, the brainchild of someone within the Evo corporation. I had an idea of what MP was but scrapped it because it honestly sounded too gonzo. Need proof? Just look up a Matrioshka brain. Yeah, I'll save that for an actual sci-fi game methinks.
The dude behind Matrioshka (whatever it is) is Alex Reed, who has unfortunately made things personal with the shadowrunners. Manipulating the technomancer's wife and the street samurai's uncle into killing the brawling adept's mother, and so on. They have no idea what the Matrioshka Project, just that this Alex Reed guy has messed with them all and needs to die.
So what exactly would Evo invest so much into from one dude, being Alex Reed? Corporations expect results and won't invest in some madman's dream if there's no results from it. The Matrioshka Project will not be a literal Matrioshka brain, but it should still be something significant. I'm thinking something about human evolution or some other transhumanist thing (being Evo and whatnot) but I'm honestly stumped for ideas.
Short story: I'm playing this is a Jason Bourne meets James Bond kinda campaign. What're your guys' thoughts? Any questions from anything I might have left out or needs more detail? Any part of this sounds outrageous by Shadowrun standards and needs revamping?