Rotten Apple is set in October 2072. Prometheus was doing that in 2071, during Emergence, along with everyone else in the world with the balls and minimal capabilities to do so.
Since then and leading into late 2075, perhaps it just proved unwise to continue dabbling in a field that the great dragon head of a AAA's R&D operations had a personal interest in, and had since invested considerable resources, beyond whatever is left and referenced in Stolen Souls. Perhaps they were a one-hit wonder that hit a brick wall because their research went down the wrong path.
Oops.
¯\_(ツ)_/¯