Honestly, in Priority, "natural" skills are cheaper. Sure, you could start out with, say, Resources: A and Skills: C, and get, let's say, a rating: 6 chipjack (120,000 Nuyen), rating: 5 skillwires with the restricted gear quality (100,000 Nuyen), and four rating: 5 activesofts (100,000 Nuyen), still leaving you enough for those rating: 3 tailored pheromones. On the other hand, you could get Skills: A and Resources: C, getting just the rating: 3 tailored pheromones - and have 18 more points for individual skills and 8 more points for skill groups. Skills that you can spend Edge on, and raise with Karma.