Mechanical downfalls aside, Alchemy also seems a lot more complicated than regular spellcasting to me. You have to roll more and keep track of all the preparations.
I agree with the others; Sam is usually a lot easier to play compared to magic, but if the whole group is new, you should probably have someone bite the bullet and make a mage.
As to how to actually get through your first build, that's a different question...
The best way, if you have the time for it, would be to just sit down and make a character. The chapter on character generation isn't that big, and you usually only really need one or two chapter besides that, depending on archetype (and not too deeply). That way you get a good feel of how the build system works and what kind of tradeoffs there are. Your first character is probably going to be terrible (everyone's is) but once you know a bit what you're doing, you can ask more directed questions, post an idea of what you'd like here and ask for comments, and start reading the relevant chapters in context.