Some things to consider is that you invest a lot of skill points on agility skills.
Agility boost is fine out of combat, but in combat it is a waste of time (unarmed is a complex action).
Damage:
16k + biocompatibility(bioware) - gives you bone density 3 + striking callus 2 (for a whooping +4 to unarmed damage) along with critical strike adept power and killing hands you'll have 11P (to be boosted to 12P if you go beast way adept and take keratin control.
Another option is to take adept spell to improve damage (e.g imprrove strength or element aura)
Yet, another power to consider is the elemental body adept power, it gives you a large bonus to hit as you only need to touch the opponent, and anyone touching you gets whooped.
Finally, it seem to be worth it to get less skill points but a muscle toner, you could easily start with Agility 10. (used muscle toner 3 and adept power) it would give you superhuman running speed to be able to cover large distances while running to punch someone. The expense of it is that you'll have less skill points but well the agility is higher to begin with.