Exactly.
But also:
If you build to a certain standard, you shouldn't be expecting to face challenges built for a lower standard. You don't see level 15s fighting 4 hit point goblins in That Other Game (tm), so neither should you expect gutter punk encounters if you're throwing 20+ dice. Sure, cyber ninja vampires filling in for gutter punks in gutter punk-appropriate encounters is bad GMing, but if cyber ninja vampires are what you're powerful enough to fight then that's what you should be getting 
My philosophy is a little different.
If I am just running/playing a murder hobo game, that doesn't focus much on role-play or character development much if at all, then I am down with that.
But most of my core group's games are half murder hobo and character optimization, and half role-play and character development. When I am running or playing a more serious minded campaign like that, I want appropriate world consistency to be part of it. A big part of world consistency for me is NPC power levels. I feel like a character with 300+ karma, or magic rating over 8, or nothing but alphaware and deltaware should be quite uncommon. You'd be talking about the elite corp forces and shit. If you encounter them, or higher, every time you do a run then it starts to feel like exceptional people are endless.
When I am running those games I save those tough fights for critical moments. When the party engages most fights, I instead use enough lower key enemies as is necessary to make them sweat a little, or I let them have a cake walk in terms of their fight. I instead threaten them by threatening what they care about. Sure, your 800 karma mage is so strong that in order to challenge it I have to whip up what amounts to some bullshit. . .but how tough is your grand daughter pal? How well protected is that new humanitarian enterprise's office building? How secure is your personal reputation vs. being dragged through the mud? Stuff like that. It makes the game more engaging while maintaining an appropriate sense that the exceptional are equally rare.
Mind you none of that really matters until several hundred karma in.