Welcome aboard fellow Canadian.
When running a run, think more Dark Heresy than D&D. There is a run with an objective: the PCs do legwork and gather info, make a plan, and do the job—while being harassed by any number of things: enemies, their Johnson, criminal organizations, police or corporate forces, or other runner groups. Give the PCs a wide range of options for completing the runs. Since you give out experience (Karma), you have more control over what characters are rewarded for. If you like more of an rp game with good legwork you can give out a bit more Karma for social events than combat (unless the combat is truly spectacular). The karma give out is normally between 6-8 a run; if runs last more than a few sessions then try for 2-4 a session with the big 6-8 payout at the end.
SR is lethal, so roll with the punches and make sure the PCs do things like grab cover and not run head first into gunfire.
Now for the Algonkian-Manitou Council (AMC) info. Winnipeg is mostly in the UCAS, but Native Americans will be a big effect.
Straight from the Sixth World Almanac:
Algonkian-Manitou: al-gän-kē-ən ma-nə-tü
Population: 5,205,000
Primary Languages: Algonkian (official), English (official), Iroquois, Sperethiel (un-recognized)
States: Algonkian Council, Manitou Council (un-recognized) Government Type: Republic, with 3 leaders (1 elected, 1 appointed, 1 hereditary)
Bordering Countries: Athabaskan Council, Quebec, Sioux, Salish-Shidhe Council, UCAS
Geography: Prairies and mountainous regions, numerous freshwater lakes, and bordering Hudson Bay
Notable Features: Cypress Hills, Hudson Bay
From Native American Nations Volume Two:
Population: 22,548,000
Human 56%
Elf 26%
Dwarf 7%
Ork 6%
Troll 4%
Other 1%
Per Capita Income: 17,000¥
Pop below poverty level: 23%
Corporate Affiliation: 19%
Big population change, so I am not sure what is up there.
The Manitou have been trying to secede while Algonkian didn't like this and grabbed support from Aztechnology hit a Manitou boat with security forces and slaughtered a bunch of people in 2061. The Manitou kept trying to secede, and during the Crash 2.0 they mounted a rebellion that ignited a very brief civil war which the Algonkian won.
Aztechnology is the largest corp in the AMC. Chiefs in the AMC over the last ten years have been assassinated or geeked in accidents. The military has control of the AMC, but the place is a smuggler's haven: the big A keeps Thunder Bay keeping the port guarded with little or no care for independants who goes through—customs are quick and efficient.
All judges are Shamans and the law is fairly equal between natives and outsiders, and reasonable firearm possession are typically lax and rarely enforced. On a local level tribal taboos and social etiquette are enforced as well as social punishments such as banishment, excommunication, and social exile.
AMC has good relations with all the nations around them, they have strong trade bonds with UCAS, Sioux Nation, and Québec, and UCAS. AMC is a pleasant place to be with friendly locals and a lot of local colour.
The best info for the Algonkian-Manitou Council is in the old source book Native American Nations Volume Two (a full 10 pages). In the 6th World Almanac there are three pages outlying the Council in 2072.