Well with DocWagon, we were always having to rescue someone. The stories behind it and the rescues themselves were varied enough to keep it interesting.
It and the Lonestar Rapid Response Team both had this feel (always extraction or neutralizing targets respectively), but by making the enemies be on a different run each time, you can add a lot of mix.
For instance, the approach as a Lonestart RRT changed drastically if the threat was a hostage crisis as opposed to a bunch of runners trying to steal some new wares from Ares Arms.
The big difference is that there is a lack of legwork going on usually (compared to most games), but it works real well for a combat oriented group.