The karma limits for stats don't count the special ones the edge/magic/res.
I used to think it was that way, too (I assumed so mainly because that is how Build Points does it). But if you read the rules carefully, the special Attributes fall under that Karma limit (375 for humans) too. Human awakened tend to get boned in Karmagen. I would actually recommend house ruling that special Attributes don't fall under the cap, because human awakened are usually the
only ones who get boned by it.
Humans, though, do tend to come out slightly better in Karmagen than they do in Build Points. A mundane human with low Edge can actually have decent core Attributes, and will be more versatile in things like skills/gear/contacts. Metahumans are more expensive, because the exponential Attribute costs make buying their Attributes up more expensive. You do save on metahumans if you don't buy up their "favored" Attributes, but that is kind of shooting yourself in the foot.
For character building advice for Karmagen, I would say:
For humans, usually you can have a decent Edge
or a decent Magic, not both.
For specialists, don't worry. You can build them, and they still usually come out ahead of what they do in Build Points.
For generalists, rejoice, because low to middle Attributes and skills are very cheap - if you don't buy either of them up high, you will be able to afford a lot more than you would under Build Points.
Knowledge skills will really test your resolve as a roleplayer, because you don't get them for free, any longer.