I used to play a few games like these, but they were not really serious ones (think about Grand Theft Auto San Andreas silliest missions to get an idea).
Character creation started with those three questions: How do the police officers call you ? How do the gang members call you ? And how do you mother call you ? Squatter lifestyle also meant "living at your mom's" (requiring the character to hide its automatic weapons under his bed) and Low was the highest lifestyle available at creation anyway.
The characters were all living in Hollywood in Redmond (aka "The Real Hollywood"). Their gang was part of the Crimson Crush, but there was some internal rivalry within the gang. There was also two subgroups within the gang : "Northside" (latino and filipino orks whose grand mother attend the catholic church north of Hollywood) and "Southside" (black ork whose grand mother attends the protestant church south of Hollywood). That North and Southside thing was only for making fun of each other and some lame display of pride (like continuously making N or S signs with your hands during the game).
At character creation, they had to pick at least one "useful" skill or specialization like Virtual Games, Basketball, Hip-hop MCing or DJing, Low-Ride Automotive Mechanics or Sound System Hardware. I actually allowed one Adept, who had his entire power set dedicated to hip-hop vocal performance.
Among other rules, they were barred from ever carrying a spare clip on them, as those keep on falling in your underwear (though they could have some in the car if heading for a drive-by shooting). I did not establish clear rules regarding availability and augmentations, but all the players kept it low level enough.
The first adventure was about stealing some simsense equipment from a pron studio to record a hip-hop concert live. In the second one, they had to intimidate someone selling a new drug called tempo in a nightclub on the gang's turf. In the third, the PC basically were contacts of a runner playing a Ghost Cartel adventure : a former member of the gang, now a pro runner, came in his SUV and told them it would be cool if they shoot some First Nations who recently started selling drugs in Northern Redmond (and create a distraction for the team by the way). And in the fourth and last game to this date, they tried to get a tempo deal the Koreans, when the First Nations stroke back.