I would say you would have to have something in your mind to actually be able to recall if nanites are going to help you for a knowledge skill test...if you're defaulting then your using the random association part of your brain rather than established neural pathways which nanites are good at reinforcing.
Ah, word. So like the Learning Stimulus nanites which lower karma cost for
improving knowledge skills under the condition that you already have some knowledge of the topic.
Well, with the 4 dice from my Intuition minus defaulting, can I just buy a hit to identify the substance and its general effects (gets you high, you see magic things?) I figure general knowledge should be able to tell me that much, rather than specific knowledge of its effects, after effects, average duration, means of cultivation, smuggling, street price and all the other things that someone truly familiar with it would know.
Basically, I would want to get an idea of what it is, then do a data search and look for possible side effects, finding the whole dual-natured thing is going to bring up the concept of wards and the problems that we're about to run into there. Namely that a dual-natured being passing through a ward has to roll charisma+magic vs the ward's forcex2 or be knocked unconscious, filling their Stun Track all the way to the top. Oh, and if they win the test against the ward, kablooey. Ward goes down and magical alarms go off.